Source: ANIMAL_MODELS

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 213
Gene Symbol: ALB
ALB
albumin 0.317 0.962 0.64
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 0.960 3 0 1989 2020
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 0.957 3 0 1997 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 1.000 2 0 2008 2020
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
cellular communication network factor 2 0.399 0.846 5.0E-04
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 0.974 2 0 1998 2020
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.321 0.962 0.61
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 0.969 2 0 2000 2020
Entrez Id: 50507
Gene Symbol: NOX4
NOX4
NADPH oxidase 4 0.471 0.885 5.8E-20
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 1.000 2 0 2005 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 1.000 2 0 2010 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 1.000 1 0 2002 2020
Entrez Id: 5972
Gene Symbol: REN
REN
renin 0.370 0.923 2.4E-07
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 0.990 1 0 1995 2020
Entrez Id: 2932
Gene Symbol: GSK3B
GSK3B
glycogen synthase kinase 3 beta 0.430 0.846 0.96
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.250 None 1.000 1 0 2013 2020
Entrez Id: 9365
Gene Symbol: KL
KL
klotho 0.448 0.769 2.2E-04
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 1.000 1 0 2012 2020
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1
hepatitis A virus cellular receptor 1 0.489 0.885 8.5E-07
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 1.000 1 0 2012 2020
Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
kelch like ECH associated protein 1 0.475 0.808 3.9E-04
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.210 None 1.000 1 0 2011 2020
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.351 0.923 0.10
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.230 None 1.000 3 0 2009 2019
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
insulin like growth factor 2 0.390 0.885 4.4E-02
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.230 None 1.000 2 0 1996 2019
Entrez Id: 177
Gene Symbol: AGER
AGER
advanced glycosylation end-product specific receptor 0.420 0.885 6.4E-16
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 0.960 2 0 2003 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 0.914 2 0 1994 2019
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
serpin family E member 1 0.359 0.885 4.4E-02
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 0.889 2 0 1996 2019
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.290 None 1.000 1 0 2013 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 0.990 1 0 1996 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
peroxisome proliferator activated receptor gamma 0.358 0.885 2.9E-02
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.600 None 0.962 1 0 2003 2019
Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
protein kinase C beta 0.453 0.885 1.00
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.270 None 1.000 1 0 2003 2019
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.381 0.923 9.7E-03
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.260 None 1.000 1 0 2011 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.260 None 1.000 1 0 2012 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
disease 0.300 None 0.923 1 0 2006 2019